Research
Bacterial stress responses, biofilms, and antimicrobial efficacy
in complex environments.
Bacterial Stress Responses and Antimicrobial Resistance
Bacterial stress responses contribute to microbial adaptation, persistence, and antibiotic resistance. Our research investigates how bacteria survive oxidative stress caused by reactive chlorine species such as bleach-derived hypochlorous acid, as well as exposure to antibiotics and other antimicrobials, and how these mechanisms influence microbial survival and persistence.
Biofilm Infections and
Chronic Wounds
Biofilms are polymicrobial communities that promote persistence, antimicrobial tolerance, and the development of chronic infections including chronic wounds. Our research investigates how microbial interactions and host immune responses contribute to biofilm-associated persistence, delayed wound healing, and antimicrobial resistance in chronic wound infections.
Tiny Earth and
Antimicrobial Discovery
Tiny Earth is an international research-based education initiative focused on the discovery of antibiotic-producing microorganisms from soil samples. Our lab investigates environmental bacteria and microbial interactions linked to antimicrobial activity, resistance and biofilms. In addition, we study antibiofilm and antimicrobial peptides as novel treatment options to fight resistant biofilm infections.